Adrafinil 300mg

Description

Adrafinil 300mg — The Legal Gateway to Modafinil-Class Eugeroics

Adrafinil (brand name: Olmifon) is a prodrug of modafinil — meaning it is metabolised by the liver into modafinil after oral ingestion. Originally developed by the French pharmaceutical company Lafon Laboratories in 1974, adrafinil was the first compound in the -afinil family to be discovered, predating modafinil by over a decade.

The key advantage of adrafinil is its legal status: unlike modafinil (which requires a prescription in most EU countries), adrafinil is classified as an unregulated compound or dietary supplement in many jurisdictions. This makes it one of the most legally accessible modafinil-class eugeroics available — working through the same metabolic pathway as modafinil.

How Adrafinil Works

Metabolic Conversion to Modafinil

After oral ingestion, adrafinil is absorbed in the gastrointestinal tract and transported to the liver, where hepatic enzymes (primarily amidase enzymes) cleave the hydroxyl group from the molecule, producing modafinil as the primary active metabolite. Approximately 60-70% of each adrafinil dose is converted to modafinil.

This means that adrafinil works through the same neurological mechanisms as modafinil. Modafinil’s pharmacology involves selective dopamine reuptake inhibition in the prefrontal cortex, histamine and orexin pathway activation that promotes wakefulness, and GABA modulation. In healthy people, adrafinil and modafinil are used off-label for wakefulness; cognitive effects vary between individuals and are not guaranteed.

Onset & Duration

Because adrafinil requires hepatic conversion before it becomes pharmacologically active, its onset is slower than direct modafinil — typically 60-90 minutes versus 30-60 minutes for modafinil tablets. Once converted, users report effects that are broadly similar to modafinil in both quality and duration (commonly 10-12 hours).

Adrafinil vs Modafinil — Key Differences

Legal Status

The most significant advantage of adrafinil is its regulatory classification. While modafinil is a prescription-only medicine (POM) in the Netherlands, Germany, France, and most EU member states, adrafinil remains unscheduled and unregulated in many of these same jurisdictions. In those countries no prescription is needed for personal import. Legal status changes and varies by country — always verify the current rules in your specific jurisdiction before ordering.

Dosing

Due to the conversion efficiency (~60-70%), a 300mg dose of adrafinil is commonly considered roughly equivalent to 200mg of modafinil. Our capsules contain exactly 300mg of pharmaceutical-grade adrafinil — one capsule is the typical single dose.

Liver Considerations

Because adrafinil is metabolised hepatically, it places more load on the liver compared to direct modafinil use. For this reason, we suggest: (1) periodic liver function monitoring for users taking adrafinil daily for more than 3 months, (2) avoiding alcohol on adrafinil days, and (3) cycling with rest days (e.g., 4 days on, 3 days off, or alternating weeks with direct modafinil). Discuss liver health with your doctor before regular use.

Who Uses Adrafinil?

• First-time users who want to explore modafinil-class compounds without navigating prescription requirements
• Users in countries where modafinil requires a prescription but adrafinil is unregulated
• Supplement-oriented users who prefer capsule-based compounds to pharmaceutical tablets
• Rotation strategy — adrafinil is often used in a rotation with modafinil and armodafinil to help manage tolerance

Dosage Guide

Commonly used dose: 300mg (1 capsule) taken in the morning on an empty stomach. First-time users: many start with 150mg (open capsule, take half) to assess individual response. Effects typically begin within 60-90 minutes and last 10-12 hours. Upper range: users generally do not exceed 600mg per 24 hours (not advised for daily use at this level). Take with a full glass of water and avoid taking after 2PM. This is general information, not medical advice — consult a doctor before use.

For more dosage information, see our dosage guide. Not sure whether adrafinil or modafinil is right for you? Try our free sample kit of standard modafinil to compare, or contact our team for personalised recommendations.

Product Specifications

• Active compound: Adrafinil (2-[(diphenylmethyl)sulfinyl]acetohydroxamic acid)
• Dose per capsule: 300mg
• Capsule type: Vegetarian (HPMC)
• Bioavailability: ~80% oral, ~60-70% conversion to modafinil
• Onset: 60-90 minutes
• Duration: 10-12 hours (once converted)
• Metabolises to: Modafinil + modafinilic acid
• Storage: Cool, dry place. Shelf life: 24 months
• Testing: Independent third-party lab testing — COA available per batch